Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep
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چکیده
منابع مشابه
Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep
Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large-animal model of emphysema using repeated LPS administration into sheep lung segments. An experimental protocol was designed to facilitate comparisons with elastase-treated and control segments within the same lung of individual shee...
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ژورنال
عنوان ژورنال: International Journal of COPD
سال: 2006
ISSN: 1176-9106
DOI: 10.2147/copd.2006.1.2.189